Visceral lipid accumulation and lipid accumulation product outperform insulin resistance score for metabolic syndrome prediction in Northern Chinese adults: validation through AUC comparison and decision curve analysis
This large-scale validation establishes LAP and VAI as superior, sex-specific predictors of MetS compared to METS-IR. LAP is optimal overall and in women, while VAI is optimal in men. Their reliance on standard clinical measurements establishes them as practical tools for metabolic risk stratification.
Authors
- Yu-Qiang Zuo (ORCID: https://orcid.org/0000-0002-8195-0651)
- Qing Liu (ORCID: https://orcid.org/0000-0002-6163-2488)
- Han Zhang (ORCID: https://orcid.org/0000-0001-9522-4418)
- Lijun Wang (ORCID: https://orcid.org/0000-0002-5613-2382)
- Xing Guan
- Zheng Wang (ORCID: https://orcid.org/0000-0001-9255-2977)
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s12902-025-02086-w
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00