Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Model
While all areas analyzed were impacted by the prenatal insults, the striatum, which consists primarily of efferent pathways, appears more vulnerable to injury compared to the PFC. Additional studies are needed to characterize the impact this may have on function related to these critical brain regions.
Authors
- Riddhi Patel (ORCID: https://orcid.org/0000-0002-0169-1224)
- Daniel D. Savage (ORCID: https://orcid.org/0000-0003-1726-1103)
- Lauren L. Jantzie (ORCID: https://orcid.org/0000-0002-5410-3553)
- Suzy Davies (ORCID: https://orcid.org/0000-0002-9992-9551)
- Hawley Helmbrecht (ORCID: https://orcid.org/0000-0002-4797-0130)
- Americo Rivera
- Jessie R. Maxwell (ORCID: https://orcid.org/0000-0001-8990-7239)
- Yasmine Baba Amer
- Zarena M. Dominguez
Institutions
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- University of New Mexico (US)
- Johns Hopkins Medicine (US)
- Johns Hopkins Children's Center (US)
Publication Details
- Journal
- Developmental Neuroscience
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1159/000549504
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism
- National Center for Advancing Translational Sciences