Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

These automated reports leverage a large database to provide accessible data for national and regional policy makers and researchers to assess the clinical consequences of different primaquine regimens in different endemic settings. The reports will inform local and regional policy decisions and research priorities in vivax-endemic areas.

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Publication Details

Journal
Malaria Journal
Published
2025-11-14
DOI
https://doi.org/10.1186/s12936-025-05642-w
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00

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article

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

Daniel Abebe Mekonnen, Philippe J. Guérin, Kavitha Saravu, Harin Karunajeewa et al.
Malaria Journal
Malaria Research and Control
article

Automated reporting of primaquine dose efficacy, tolerability and safety for Plasmodium vivax malaria using a systematic review and individual patient data meta-analysis

Daniel Abebe Mekonnen, Philippe J. Guérin, Kavitha Saravu, Harin Karunajeewa, Liwang Cui, Sasithon Pukrittayakamee, Tamiru Shibiru Degaga, Tesfay Abreha, Laurens Manning, Nguyễn Hoàng Châu, Ishag Adam, Prakash Ghimire, Mohammad Shafiul Alam, Margarete do Socorro Mendonça Gomes, Ric N. Price, Ghulam Rahim Awab, Sarah Boyd, Wuelton Marcelo Monteiro, Komal Raj Rijal, Lorenz von Seidlein, Marcelo U. Ferreira, Nicholas M. Anstey, Dhélio B. Pereira, Nicholas Day, Nathália Nogueira Chamma-Siqueira, Jetsumon Sattabongkot, Charles J. Woodrow, Larissa W. Brasil, Sze-Ann Woon, Simone Ladeia-Andrade, Walter Taylor, Timothy William, Mark Rowland, Annette Erhart, Matthew J. Grigg, Bridget E. Barber, Benedikt Ley, Suéllen Dias Negreiros, Arjen M. Dondorp, Ayodhia Pitaloka Pasaribu, Ashenafi Assefa, Brioni R. Moore, Rhea J. Longley, Bipin Adhikari, Inge Sutanto, Gavin Koh, Julie Anne Simpson, André Bastos Daher, Cindy S. Chu, Anielle de Pina-Costa, Kartini Lidia, André M. Siqueira, Erni Juwita Nelwan, Jeanne Rini Poespoprodjo, Lilia González-Cerón, Guilherme Suarez‐Kurtz, Pham Vinh Thanh, Justin A. Green, Asnakew K. Yeshiwondim, Wasif Ali Khan, Fitsum G. Tadesse, Giselle Maria Rachid Viana, Nicholas John White, Jimee Hwang, Robert J. Commons, Megha Rajasekhar, Alejandro Llanos‐Cuentas, José Luiz Fernandes Vieira, David J. Price, Kamala Thriemer, Peta Edler, Mohammad Nader Naadim, Rishikesh Kumar, Lina Zuluaga-Idárraga, Endalamaw Gadisa, François Nosten, Marcus V. G. Lacerda, Ivo Mueller, Asrat Hailu Mekuria, Najia Karim Ghanchi, Toby Leslie, Adugna Woyessa, J. Kevin Baird, Mohammad Anwar Hassanzai
article en

Abstract

These automated reports leverage a large database to provide accessible data for national and regional policy makers and researchers to assess the clinical consequences of different primaquine regimens in different endemic settings. The reports will inform local and regional policy decisions and research priorities in vivax-endemic areas.

Malaria JournalVol. 24(1)
University of North Carolina at Chapel Hill (US), Aga Khan University (PK), Universidade Federal de Rondônia (BR), Centers for Disease Control and Prevention (US), World Health Organization - Pakistan (PK), WWF Colombia (CO), Rajendra Memorial Research Institute of Medical Sciences (IN), Haramaya University (ET), Tribhuvan University (NP), Qassim University (SA), Universidade Federal Fluminense (BR), Manipal Academy of Higher Education (IN), Universitas Gadjah Mada (ID), The University of Melbourne (AU), The Kids Research Institute Australia (AU), The University of Western Australia (AU), Universidade de São Paulo (BR), GlaxoSmithKline (United Kingdom) (GB), Walter and Eliza Hall Institute of Medical Research (AU), Universidad Peruana Cayetano Heredia (PE), Curtin University (AU), International Centre for Diarrhoeal Disease Research (BD), Universidade do Estado do Pará (BR), QIMR Berghofer Medical Research Institute (AU), Mahidol University (TH), Universitas Sumatera Utara (ID), University of South Florida (US), Royal Brisbane and Women's Hospital (AU), Royal Perth Hospital (AU), Fiona Stanley Hospital (AU), Northwick Park Hospital (GB), University of Indonesia (ID), Charles Darwin University (AU), University of Nusa Cendana (ID), Universidad de Antioquia (CO), University of Oxford (GB), Menzies School of Health Research (AU), Fundação de Medicina Tropical (BR), London School of Hygiene & Tropical Medicine (GB), Shoklo Malaria Research Unit (TH), Ethiopian Public Health Institute (ET), Centro Universitário do Pará (BR), Peter Doherty Institute (AU), U.S. President's Malaria Initiative (US), Ballarat Health Services (AU), Western Health (AU), MRC Unit the Gambia (GM), Mahidol Oxford Tropical Medicine Research Unit (TH), Health Protection and Research Organisation (AF), GlaxoSmithKline (Sri Lanka) (LK), Universidade Federal do Amapá (BR), World Health Organization - Afghanistan (AF), Secretaria da Saúde (BR), Instituto Nacional de Câncer - INCA (BR), Worldwide Veterinary Service (GB), Instituto Evandro Chagas (BR), Universidade Estadual do Amapá (BR), Subang Jaya Medical Centre (MY), Universidade do Estado do Amazonas (BR), GlaxoSmithKline (Germany) (DE), Oxford University Clinical Research Unit (VN), National Institute of Malariology, Parasitology and Entomology (VN), Ministério da Saúde (ST), Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID), Hospital for Tropical Diseases (VN), Infectious Diseases Data Observatory (GB), Armauer Hansen Research Institute (ET), Universidade Cruzeiro do Sul (BR), Queen Elizabeth Hospital (MY), Instituto de Investigação Científica Tropical (PT), Arba Minch University (ET), Oxford University Clinical Research Unit Indonesia, Addis Ababa University (ET), Fundação Oswaldo Cruz (BR), The University of Texas Medical Branch at Galveston (US), Universidade Federal do Pará (BR), Universidade Federal do Amazonas (BR), Kasturba Medical College, Manipal (IN), University of Gondar (ET), Companhia Energética de Minas Gerais (Brazil) (BR)
GlaxoSmithKline, World Health Organization, London School of Hygiene and Tropical Medicine, Universidad Internacional de La Rioja, Tribhuvan University, Kasturba Medical College, Manipal, University of Oxford, Indian Council of Medical Research, Curtin University of Technology, Mahidol University, China Scholarship Council, Haramaya University, Universidad de Antioquia, Universidade de São Paulo, Universidade de Lisboa, Universitas Indonesia, Fundação Oswaldo Cruz, Universidade Federal do Pará, University of Gondar, Addis Ababa University, Universitas Gadjah Mada, Universitas Sumatera Utara, Universidade do Estado do Amazonas, Fiona Stanley Hospital, Centers for Disease Control and Prevention, University of North Carolina at Chapel Hill, President's Malaria Initiative, Medical Research Council, National Health and Medical Research Council, Faculty of Tropical Medicine, Mahidol University, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Mailman School of Public Health, Columbia University
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