Design, synthesis, in silico studies, molecular docking, ADMET and anticancer activity of novel <i>N</i> -substituted-4-pyrazole derivatives

The activity of synthesized 1 H-substituted carbothioamide pyrazole derivatives was increased when added to thiazole with different electron-withdrawing groups.

Authors

Margret M. Girges
Hager G. El-kasabi
Ahmed Fikry El-Sayed (ORCID: https://orcid.org/0000-0002-5312-4870)
Ghada E. Abdel‐Ghani

Institutions

Mansoura University (EG)
Egypt Center for Research and Regenerative Medicine (EG)
National Research Centre (EG)

Publication Details

Journal: Future Medicinal Chemistry
Published: 2025-11-14
DOI: https://doi.org/10.1080/17568919.2025.2575750
Citations: 1
Primary Topic: Synthesis and biological activity
Type: article
Field-Weighted Citation Impact: 0.94

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article

Design, synthesis, in silico studies, molecular docking, ADMET and anticancer activity of novel N -substituted-4-pyrazole derivatives

Margret M. Girges, Hager G. El-kasabi, Ahmed Fikry El-Sayed, Ghada E. Abdel‐Ghani

Nov 14, 2025

1 citations

Future Medicinal Chemistry

Synthesis and biological activity

0.94

article

Design, synthesis, in silico studies, molecular docking, ADMET and anticancer activity of novel N -substituted-4-pyrazole derivatives

Margret M. Girges, Hager G. El-kasabi, Ahmed Fikry El-Sayed, Ghada E. Abdel‐Ghani

November 14, 2025article en

1 citations

Abstract

The activity of synthesized 1 H-substituted carbothioamide pyrazole derivatives was increased when added to thiazole with different electron-withdrawing groups.

Future Medicinal ChemistryVol. 17(23)

Mansoura University (EG), Egypt Center for Research and Regenerative Medicine (EG), National Research Centre (EG)

Openalex Percentile: Top 20%

Synthesis and biological activity

0.94

DOI Source OpenAlex

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Design, synthesis, in silico studies, molecular docking, ADMET and anticancer activity of novel <i>N</i> -substituted-4-pyrazole derivatives — Margret M. Girges, Hager G. El-kasabi, et al. · Future Medicinal Chemistry (2025) | TGRS Research Map | TGRS