A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole
The genus <i>Alternaria</i> comprises several species of dematiaceous hyphomycetes known to cause opportunistic infections in humans. Over the past two decades, fungal infections have emerged as a significant cause of morbidity and mortality, particularly among immunocompromised individuals. Such infections often occur following disruption of the skin or corneal epithelial barrier, especially in patients with pre-existing ocular conditions or compromised immune status. This case report describes a rare instance of fungal keratitis (FK) caused by <i>Alternaria citri</i> in a 71-year-old male who presented with an acute onset of eye infection. The patient showed a favorable response to treatment with voriconazole.
Authors
- Silvia Crotti (ORCID: https://orcid.org/0000-0002-4798-1964)
- Chiara Poletti
- Alessandra Caracciolo
- Massimo Busin (ORCID: https://orcid.org/0000-0003-3635-3521)
- Deborah Cruciani (ORCID: https://orcid.org/0000-0003-2155-4742)
- Giorgia Boaretto (ORCID: https://orcid.org/0000-0002-1994-6272)
- E. Mariotti Zani
- Cristina Lapucci
- Maura Bertazzolo
- Roberta Vatri
Institutions
- Ospedale degli Infermi (IT)
- Institut Belge pour la Sécurité Routière (BE)
- Presidio Ospedaliero (IT)
- Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche (IT)
Publication Details
- Journal
- Journal of Fungi
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3390/jof11110805
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00