A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole

The genus <i>Alternaria</i> comprises several species of dematiaceous hyphomycetes known to cause opportunistic infections in humans. Over the past two decades, fungal infections have emerged as a significant cause of morbidity and mortality, particularly among immunocompromised individuals. Such infections often occur following disruption of the skin or corneal epithelial barrier, especially in patients with pre-existing ocular conditions or compromised immune status. This case report describes a rare instance of fungal keratitis (FK) caused by <i>Alternaria citri</i> in a 71-year-old male who presented with an acute onset of eye infection. The patient showed a favorable response to treatment with voriconazole.

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Publication Details

Journal
Journal of Fungi
Published
2025-11-13
DOI
https://doi.org/10.3390/jof11110805
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole

Silvia Crotti, Chiara Poletti, Alessandra Caracciolo, Massimo Busin et al.
Journal of Fungi
Ocular Infections and Treatments
article

A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole

Silvia Crotti, Chiara Poletti, Alessandra Caracciolo, Massimo Busin, Deborah Cruciani, Giorgia Boaretto, E. Mariotti Zani, Cristina Lapucci, Maura Bertazzolo, Roberta Vatri
article en

Abstract

The genus <i>Alternaria</i> comprises several species of dematiaceous hyphomycetes known to cause opportunistic infections in humans. Over the past two decades, fungal infections have emerged as a significant cause of morbidity and mortality, particularly among immunocompromised individuals. Such infections often occur following disruption of the skin or corneal epithelial barrier, especially in patients with pre-existing ocular conditions or compromised immune status. This case report describes a rare instance of fungal keratitis (FK) caused by <i>Alternaria citri</i> in a 71-year-old male who presented with an acute onset of eye infection. The patient showed a favorable response to treatment with voriconazole.

Journal of FungiVol. 11(11)
Ospedale degli Infermi (IT), Institut Belge pour la Sécurité Routière (BE), Presidio Ospedaliero (IT), Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche (IT)
Openalex Percentile: Top 52%
Ocular Infections and Treatments
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A Rare Case of Alternaria citri Keratitis Successfully Treated with Voriconazole — Silvia Crotti, Chiara Poletti, et al. · Journal of Fungi (2025) | TGRS Research Map | TGRS