Alpha-linolenic acid reshapes the gastrointestinal ecology to enhance immune function in dairy cows: insights from microbiome and metabolome profiling
These findings indicate that high dietary ALA reshapes gastrointestinal microbiota and attenuates inflammatory responses by inhibiting microbial-metabolite-driven arachidonic acid metabolism, thereby enhancing immune regulation in dairy cows.
Authors
- Yangyi Hao (ORCID: https://orcid.org/0000-0002-7160-3103)
- Hongjin Ji
- Zhijun Cao (ORCID: https://orcid.org/0000-0002-5519-9462)
- Shengli Li (ORCID: https://orcid.org/0000-0001-5430-303X)
- Wei Wang (ORCID: https://orcid.org/0000-0002-3741-8422)
- Hongjian Yang
- Zhantao Yang
- Yajing Wang (ORCID: https://orcid.org/0000-0002-3605-8437)
Institutions
- China Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-11-14
- DOI
- https://doi.org/10.3389/fmicb.2025.1687786
- Citations
- 1
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.12