Comments on the Series of A.P. Kozlov’s Articles “The Theory of the Evolutionary Role of Inheritable Tumors (Carcino-Evo-Devo): History of Development and Current State” in Four Parts, Published in the Journal Uspekhi Sovremennoi Biologii in 2024

A.M. Pivovarov, Ph.D., co-author of domestic preparations of recombinant human erythropoietin “Epocrin” and “Eralfon,” preparations of natural and recombinant interferon-a (“Interlock,” “Reaferon”), recombinant epidermal growth factor, and many enzyme immunoassay systems for human cytokines, gives his comments on the series of A.P. Kozlov’s articles. He notes that the discovery in the laboratory of A.P. Kozlov and co-authors of a whole class of genes with a wide tumor-specific expression makes it possible to develop therapeutic MCAs with a wide antitumor spectrum of action. Thus, the study of proteins encoded by TSEEN genes may become a new field of medical biotechnology, claiming to be universal.