Treatment patterns and long-term outcomes in anti-VEGF-treated macular oedema secondary to retinal vein occlusion: a retrospective observational study
VA improvements were observed soon after anti-VEGF treatment, but were lower with longer follow-up through 60 months, alongside lower annual injection numbers, suggesting that current single-target intravitreal anti-VEGFs may not be sufficiently durable for long-term RVO management in routine practice.
Authors
- Balasubramanian Ramasamy
- Insaf Saffar (ORCID: https://orcid.org/0000-0002-6340-557X)
- Alice V. R. Lake (ORCID: https://orcid.org/0000-0002-6341-8661)
- Emily Fletcher (ORCID: https://orcid.org/0000-0001-6138-2151)
- Liliana Pereira (ORCID: https://orcid.org/0000-0001-5901-6064)
- Yinka Osoba
- Faruque Ghanchi (ORCID: https://orcid.org/0000-0002-4448-8162)
- Anne-Cecile Retiere
- Louise Downey (ORCID: https://orcid.org/0000-0001-5944-3437)
- Aires Lobo
- James Talks (ORCID: https://orcid.org/0000-0001-6126-6476)
- R J Antcliff
- Pablo Arrisi
- Antony Parker
- Colin Jones (ORCID: https://orcid.org/0000-0001-8283-3134)
- Ashish Patwardhan
- Andrew Lotery (ORCID: https://orcid.org/0000-0001-5541-4305)
- Indra Dias
- C. Gloria (ORCID: https://orcid.org/0000-0001-5657-5979)
- Christiana Dinah (ORCID: https://orcid.org/0000-0002-0815-4771)
- Sheena George (ORCID: https://orcid.org/0000-0002-9953-1834)
- Serena Salvatore
- C Brand (ORCID: https://orcid.org/0000-0003-2922-0827)
- Melanie Dodds (ORCID: https://orcid.org/0009-0007-8748-5299)
Institutions
- University of the West of England (GB)
- University of Hull (GB)
- Royal Cornwall Hospital Trust (GB)
- Royal Cornwall Hospital (GB)
- Norfolk and Norwich University Hospitals NHS Foundation Trust (GB)
- Luton and Dunstable University Hospital NHS Foundation Trust (GB)
- London North West Healthcare NHS Trust (GB)
- University Hospitals Bristol NHS Foundation Trust (GB)
- Seacroft Hospital (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Gloucestershire Hospitals NHS Foundation Trust (GB)
- Hillingdon Hospital (GB)
- Calderdale and Huddersfield NHS Foundation Trust (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Bristol Hospital (US)
- Roche (United Kingdom) (GB)
- Torbay and South Devon NHS Foundation Trust (GB)
- Royal United Hospital Bath NHS Trust (GB)
- Wirral University Teaching Hospital NHS Foundation Trust (GB)
- Bradford Teaching Hospitals NHS Foundation Trust (GB)
- University of Southampton (GB)
Publication Details
- Journal
- Eye
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1038/s41433-025-04089-2
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- F. Hoffmann-La Roche
- Genentech