Diverging global incidence trends of early-onset cancers: comparisons with incidence trends of later-onset cancers and mortality trends of early-onset cancers
The increase in many early-onset cancer types was significantly higher than that of later-onset cancers, and the incidence and mortality of certain early-onset cancer types (such as colorectal cancer) increased simultaneously. Our study highlights global differences in cancer incidence and mortality trends of early-onset and later-onset cancers.
Authors
- Tomotaka Ugai (ORCID: https://orcid.org/0000-0003-0182-5269)
- Satoko Ugai (ORCID: https://orcid.org/0009-0001-9661-9363)
- Kota Nakayama (ORCID: https://orcid.org/0009-0006-5417-3849)
- Minkyo Song (ORCID: https://orcid.org/0000-0002-9412-2871)
- Naoko Sasamoto (ORCID: https://orcid.org/0000-0002-4526-2181)
- Shizuo SHIRAI
- Hideo Matsui (ORCID: https://orcid.org/0000-0002-6638-7389)
- Hwa‐Young Lee (ORCID: https://orcid.org/0000-0003-2591-1436)
- Ichiro Kawachi (ORCID: https://orcid.org/0000-0003-3579-4456)
- Hiroki Mizuno (ORCID: https://orcid.org/0000-0002-7493-8195)
- S. Tanaka (ORCID: https://orcid.org/0009-0006-6409-7683)
- Edward Giovannucci
- Miyu Terashima (ORCID: https://orcid.org/0009-0000-2150-517X)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Okayama University (JP)
- Fred Hutch Cancer Center (US)
- Prevention Group (US)
- Dana-Farber/Harvard Cancer Center (US)
- National Institute on Aging (US)
- Harvard Global Health Institute (US)
- National Cancer Research Institute (GB)
- Massachusetts Institute of Technology (US)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Military Medical Research
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s40779-025-00670-8
- Citations
- 2
- Primary Topic
- Multiple and Secondary Primary Cancers
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Prevent Cancer Foundation
- Brigham and Women's Hospital
- Japan Society for the Promotion of Science