Contralateral breast cancer after radiotherapy and hormone therapy in two cohorts of US breast cancer survivors
Radiotherapy increased contralateral breast cancer risk, but hormone therapy appeared to mitigate this risk for ER+ cases. These findings have important implications for individuals exposed to chest radiation.
Authors
- Jacqueline B. Vo (ORCID: https://orcid.org/0000-0001-8891-4437)
- Monjoy Saha (ORCID: https://orcid.org/0000-0002-6470-3544)
- Matthew M. Mille (ORCID: https://orcid.org/0000-0003-2529-1409)
- Susan A. Smith (ORCID: https://orcid.org/0000-0002-6367-3080)
- Sheila Weinmann (ORCID: https://orcid.org/0000-0002-7696-0070)
- Clara Bodelón (ORCID: https://orcid.org/0000-0002-6578-2678)
- Rochelle E. Curtis (ORCID: https://orcid.org/0000-0002-7883-5652)
- Heather Spencer Feigelson (ORCID: https://orcid.org/0000-0001-6691-3740)
- Gretchen L. Gierach (ORCID: https://orcid.org/0000-0002-0165-5522)
- Erin J. Aiello Bowles (ORCID: https://orcid.org/0000-0001-6287-7391)
- Amy Berrington de González (ORCID: https://orcid.org/0000-0002-7332-8387)
- Cody Ramin (ORCID: https://orcid.org/0000-0002-2007-2840)
- Lene H. S. Veiga (ORCID: https://orcid.org/0000-0002-6537-1481)
- Rebecca Howell (ORCID: https://orcid.org/0000-0002-1718-8930)
- Choonsik Lee (ORCID: https://orcid.org/0000-0002-7861-8164)
- Diana S.M. Buist
Institutions
- Cedars-Sinai Medical Center (US)
- American Cancer Society (US)
- Kaiser Permanente (US)
- The University of Texas MD Anderson Cancer Center (US)
- Institute of Cancer Research (GB)
- Kaiser Permanente Washington Health Research Institute (US)
- University of Washington (US)
- Kaiser Permanente Center for Health Research (US)
- National Cancer Institute (US)
- Mercer Island School District (US)
- Division of Cancer Epidemiology and Genetics
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1038/s41416-025-03240-w
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kaiser Permanente
- RTI International
- National Institutes of Health
- National Cancer Institute