Retroperitoneal neuroglial heterotopia in infancy: case report and review of literature

Neuroglial heterotopia (NH) is a rare entity which is composed of displaced masses of mature central neuroepithelial tissue manifesting in locations unconnected to the brain and spinal cord. NH is reported in the head and neck region, most commonly in the nose and nasopharynx, but some other rare sites, such as lung, extremities, and skin are also reported. NH presenting in the retroperitoneum and during infancy is extremely rare. We present a case of an infant who presented with lump abdomen and respiratory tract infection. Imaging revealed a large retroperitoneal tumour, which was safely excised. Histopathology revealed features of NH which was further confirmed by immunohistochemistry.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1093/jscr/rjaf893
Primary Topic
Teratomas and Epidermoid Cysts
Type
article
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article

Retroperitoneal neuroglial heterotopia in infancy: case report and review of literature

Hemonta Kumar Dutta, Prasun Kumar Das, Rishiraj Baruah, Diganta Saikia et al.
Journal of Surgical Case Reports
Teratomas and Epidermoid Cysts
article

Retroperitoneal neuroglial heterotopia in infancy: case report and review of literature

Hemonta Kumar Dutta, Prasun Kumar Das, Rishiraj Baruah, Diganta Saikia, Pallav Chowlu
article en

Abstract

Neuroglial heterotopia (NH) is a rare entity which is composed of displaced masses of mature central neuroepithelial tissue manifesting in locations unconnected to the brain and spinal cord. NH is reported in the head and neck region, most commonly in the nose and nasopharynx, but some other rare sites, such as lung, extremities, and skin are also reported. NH presenting in the retroperitoneum and during infancy is extremely rare. We present a case of an infant who presented with lump abdomen and respiratory tract infection. Imaging revealed a large retroperitoneal tumour, which was safely excised. Histopathology revealed features of NH which was further confirmed by immunohistochemistry.

Journal of Surgical Case ReportsVol. 2025(11)
Regional Medical Research Centre (IN), Assam Medical College (IN)
Openalex Percentile: Top 47%
Teratomas and Epidermoid Cysts
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Retroperitoneal neuroglial heterotopia in infancy: case report and review of literature — Hemonta Kumar Dutta, Prasun Kumar Das, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS