Progressive myalgia as the sole manifestation of cancer-associated myositis: A case report and review of the literature

This case underscores the importance of considering CAM in patients with unexplained symmetrical proximal muscle pain, even in the absence of typical extramuscular symptoms. The detection of myositis-specific autoantibodies is critical for accurate diagnosis. Early identification and treatment of the underlying malignancy can significantly improve prognosis. Future research should focus on elucidating the pathogenesis of CAM, identifying more specific biomarkers, and developing standardized diagnostic and therapeutic guidelines to enhance early diagnosis and treatment outcomes.

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Publication Details

Journal
Medicine
Published
2025-11-14
DOI
https://doi.org/10.1097/md.0000000000046170
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.00
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article

Progressive myalgia as the sole manifestation of cancer-associated myositis: A case report and review of the literature

Sui Peng, Xiuqing Huang, Jian Xu
Medicine
Inflammatory Myopathies and Dermatomyositis
article

Progressive myalgia as the sole manifestation of cancer-associated myositis: A case report and review of the literature

Sui Peng, Xiuqing Huang, Jian Xu
article en

Abstract

This case underscores the importance of considering CAM in patients with unexplained symmetrical proximal muscle pain, even in the absence of typical extramuscular symptoms. The detection of myositis-specific autoantibodies is critical for accurate diagnosis. Early identification and treatment of the underlying malignancy can significantly improve prognosis. Future research should focus on elucidating the pathogenesis of CAM, identifying more specific biomarkers, and developing standardized diagnostic and therapeutic guidelines to enhance early diagnosis and treatment outcomes.

MedicineVol. 104(46)
Fudan University (CN), Wenzhou Medical University (CN), Quzhou City People's Hospital (CN), Quzhou University (CN), Huashan Hospital (CN)
Openalex Percentile: Top 55%
Inflammatory Myopathies and Dermatomyositis
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