Efficacy of different drug treatment regimens in acute asthma in children in North China: A meta-analysis

The combination of glucocorticoids and β2 receptor adrenergic agonists in acute asthma treatment in children may provide improved therapeutic outcomes compared to monotherapy, with potentially higher treatment effectiveness and shorter symptom relief time. However, these findings should be interpreted with caution due to the small number of included studies, significant heterogeneity in some outcomes, and limited long-term data. Further, high-quality studies with larger sample sizes and longer follow-up periods are needed to establish definitive recommendations for clinical practice.

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Publication Details

Journal
Medicine
Published
2025-11-14
DOI
https://doi.org/10.1097/md.0000000000045521
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of different drug treatment regimens in acute asthma in children in North China: A meta-analysis

Tingting Ma, Lihua Luo, Xiaoqian Ma, Hong Jiang
Medicine
Asthma and respiratory diseases
article

Efficacy of different drug treatment regimens in acute asthma in children in North China: A meta-analysis

Tingting Ma, Lihua Luo, Xiaoqian Ma, Hong Jiang
article en

Abstract

The combination of glucocorticoids and β2 receptor adrenergic agonists in acute asthma treatment in children may provide improved therapeutic outcomes compared to monotherapy, with potentially higher treatment effectiveness and shorter symptom relief time. However, these findings should be interpreted with caution due to the small number of included studies, significant heterogeneity in some outcomes, and limited long-term data. Further, high-quality studies with larger sample sizes and longer follow-up periods are needed to establish definitive recommendations for clinical practice.

MedicineVol. 104(46)
Capital Medical University (CN), Beijing Shijitan Hospital (CN)
Openalex Percentile: Top 58%
Asthma and respiratory diseases
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