Investigating the association between anthropometry and colorectal cancer survival: a two-sample Mendelian randomization analysis
Despite the limitations of cancer survival research, our findings support that CRC cases should avoid obesity. Further research should inform the development of recommendations targeting overweight/obesity management during cancer surveillance.
Authors
- Sarah J. Lewis (ORCID: https://orcid.org/0000-0003-4311-6890)
- Amanda I. Phipps (ORCID: https://orcid.org/0000-0002-1446-2201)
- Verena Zuber (ORCID: https://orcid.org/0000-0001-9827-1877)
- Loı̈c Le Marchand (ORCID: https://orcid.org/0000-0001-5013-980X)
- Ulrike Peters (ORCID: https://orcid.org/0000-0001-5666-9318)
- Philip Haycock (ORCID: https://orcid.org/0000-0001-5001-3350)
- Richard Michael Martin (ORCID: https://orcid.org/0000-0002-7992-7719)
- Andrew T. Chan (ORCID: https://orcid.org/0000-0001-7284-6767)
- Anna H. Wu (ORCID: https://orcid.org/0000-0003-0546-902X)
- Marc J. Gunter (ORCID: https://orcid.org/0000-0001-5472-6761)
- Emmanouil Bouras (ORCID: https://orcid.org/0000-0003-1489-5506)
- Alicja Wolk (ORCID: https://orcid.org/0000-0001-7387-6845)
- Katharina Nimptsch (ORCID: https://orcid.org/0000-0001-7877-205X)
- Afroditi Kanellopoulou (ORCID: https://orcid.org/0000-0003-2448-3548)
- Konstantinos K Tsilidis
- Fränzel J.B. van Duijnhoven
Institutions
- Broad Institute (US)
- University of Southern California (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Hawaii Pacific University (US)
- University of Ioannina (GR)
- University of Washington (US)
- Max Delbrück Center (DE)
- University Hospitals Bristol NHS Foundation Trust (GB)
- Karolinska Institutet (SE)
- University of Bristol (GB)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- Cancer Center of Hawaii (US)
- UK Dementia Research Institute (GB)
- Centre international de recherche sur le cancer (FR)
- Imperial College London (GB)
- Wageningen University & Research (NL)
Publication Details
- Journal
- International Journal of Epidemiology
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1093/ije/dyaf193
- Citations
- 2
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- NIHR Bristol Biomedical Research Centre
- Cancer Research UK
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Bristol