The Association between Genetically Predicted C-Reactive Protein Levels and Risk of Colorectal Cancer in an East Asian Population: Two-Sample Mendelian Randomization
Our findings suggest that CRP is unlikely to be a key determinant of colorectal carcinogenesis, aligning with prior studies in European populations.
Authors
- Sun‐Seog Kweon (ORCID: https://orcid.org/0000-0003-2378-8550)
- Aesun Shin (ORCID: https://orcid.org/0000-0002-6426-1969)
- Jung-Ho Yang (ORCID: https://orcid.org/0000-0002-1581-8425)
- Sun Ha Jee (ORCID: https://orcid.org/0000-0001-9519-3068)
- Jeongseon Kim (ORCID: https://orcid.org/0000-0002-0889-2686)
- Wei‐Hua Jia (ORCID: https://orcid.org/0000-0002-0528-8715)
- Keitaro Matsuo (ORCID: https://orcid.org/0000-0003-1761-6314)
- Chang Kyun Choi (ORCID: https://orcid.org/0000-0002-8257-3114)
- Min‐Ho Shin (ORCID: https://orcid.org/0000-0002-2217-5624)
- Koichi Matsuda (ORCID: https://orcid.org/0000-0001-7292-2686)
- Yu‐Tang Gao (ORCID: https://orcid.org/0000-0003-3904-1777)
- Xiao‐Ou Shu (ORCID: https://orcid.org/0000-0002-0711-8314)
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1226-070X)
- Dong-Hyun Kim (ORCID: https://orcid.org/0000-0002-1492-5253)
- Sang‐Hee Cho (ORCID: https://orcid.org/0000-0002-7995-7862)
Institutions
- Chonnam National University (KR)
- Seoul National University (KR)
- Hallym University (KR)
- Sun Yat-sen University (CN)
- Cancer Research Institute (US)
- Yonsei University (KR)
- Vanderbilt University (US)
- Hallym Polytechnic University (KR)
- New Generation University College (ET)
- National Cancer Center (US)
- Chonnam National University Hospital (KR)
- Korea Health Promotion Institute (KR)
- Shanghai Cancer Institute (CN)
- National Cancer Center (KR)
- Aichi Cancer Center (JP)
- State Key Laboratory of Oncogene and Related Genes (CN)
- Sun Yat-sen University Cancer Center (CN)
- Chonnam National University Hwasun Hospital (KR)
- Nagoya University (JP)
- The University of Tokyo (JP)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Cancer Epidemiology Biomarkers & Prevention
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1158/1055-9965.epi-25-1230
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00