Generation of hTERT-immortalized human mesenchymal stromal cells with optical and magnetic labels for in vivo transplantation and tracking
The experimental results indicate that the use of two complementary labels allows for the multimodal visualization of the derived cells post-transplantation into the rat brain striatum, which is promising for monitoring MSCs-based therapy.
Authors
- Alexey D. Bocharnikov (ORCID: https://orcid.org/0009-0006-1359-4495)
- М. V. Gulyaev (ORCID: https://orcid.org/0000-0003-4684-2484)
- Daria D. Namestnikova (ORCID: https://orcid.org/0000-0001-6635-511X)
- Maria V. Efremova (ORCID: https://orcid.org/0000-0002-5196-5596)
- Anna N. Gabashvili (ORCID: https://orcid.org/0000-0002-4251-3002)
- Petr I. Nikitin (ORCID: https://orcid.org/0000-0003-1573-5512)
- Irina B. Pevzner (ORCID: https://orcid.org/0000-0001-5048-1234)
- Stepan Vodopyanov (ORCID: https://orcid.org/0000-0003-1429-9835)
- П. И. Макаревич (ORCID: https://orcid.org/0000-0001-8869-5190)
- Viktoria A. Sarkisova
- Natalya Alexandrushkina (ORCID: https://orcid.org/0000-0003-4946-7843)
- Tatiana Tarasova (ORCID: https://orcid.org/0000-0001-8042-7079)
- Anastasiya V. Ryabova
Institutions
- Engelhardt Institute of Molecular Biology (RU)
- Peoples' Friendship University of Russia (RU)
- Albert Einstein College of Medicine (US)
- Lomonosov Moscow State University (RU)
- Pirogov Russian National Research Medical University (RU)
- Ministry of Health of the Russian Federation (RU)
- Moscow Regional Psychiatry Hospital No.5 (RU)
- Moscow State University (TJ)
- Prokhorov General Physics Institute (RU)
- Federal Medical-Biological Agency (RU)
- Eindhoven University of Technology (NL)
- National Research Nuclear University MEPhI (RU)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s13287-025-04748-x
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation