Notum disrupts Wnt/β-catenin-mediated BMP9 osteogenesis in MSCs: implications for bone regeneration
NOTUM serves as a novel regulator of BMP9-Induced osteogenesis via modulation of the Wnt/β-Catenin Axis, Suggesting its potential as a therapeutic target for bone regeneration.
Authors
- 重樹 乾
- Yumei Wang (ORCID: https://orcid.org/0000-0003-1217-9725)
- Xinyue Wan (ORCID: https://orcid.org/0000-0002-4507-2011)
- Zhenghao Xu (ORCID: https://orcid.org/0000-0003-0033-525X)
- HU Ya
- Wen-Ge He (ORCID: https://orcid.org/0000-0001-9996-5053)
- Liang Chen (ORCID: https://orcid.org/0000-0001-7303-6176)
Institutions
- Chongqing University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Cancer Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Connective Tissue Research
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1080/03008207.2025.2582827
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00