Comparing fentanyl and dexmedetomidine as adjuvants to bupivacaine for spinal anesthesia in appendectomy: effects on peritoneal symptoms – a randomized clinical trial
Dexmedetomidine provides superior peritoneal symptom control and prolonged analgesia compared to fentanyl as an intrathecal adjuvant in spinal anesthesia for appendectomy. Despite a higher incidence of bradycardia, its opioid-sparing benefits and overall safety make it a valuable alternative, particularly for procedures involving significant visceral manipulation.
Authors
- Ahmed Mahmoud (ORCID: https://orcid.org/0000-0003-2079-3629)
- Samar M. Hammad (ORCID: https://orcid.org/0000-0002-1313-2542)
- Ahmed M. Hagag (ORCID: https://orcid.org/0000-0002-3372-7885)
- Mohammed Ahmed Alazhary
- Tarek S. Hemaida (ORCID: https://orcid.org/0000-0003-0255-6339)
- Ayman Mohamady Eldemrdash (ORCID: https://orcid.org/0000-0002-8096-6686)
Institutions
- Aswan University (EG)
Publication Details
- Journal
- Perioperative Medicine
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1186/s13741-025-00618-5
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00