Agentic AI: a comprehensive survey of architectures, applications, and future directions

Abstract Agentic AI represents a transformative shift in artificial intelligence, but its rapid advancement has led to a fragmented understanding, often conflating modern neural systems with outdated symbolic models—a practice known as conceptual retrofitting . This survey cuts through this confusion by introducing a novel dual-paradigm framework that categorizes agentic systems into two distinct lineages: the symbolic/classical (relying on algorithmic planning and persistent state) and the neural/generative (leveraging stochastic generation and prompt-driven orchestration). Through a systematic PRISMA-based review of 90 studies (2018–2025), we provide a comprehensive analysis structured around this framework across three dimensions: (1) the theoretical foundations and architectural principles defining each paradigm; (2) domain-specific implementations in healthcare, finance, and robotics, demonstrating how application constraints dictate paradigm selection; and (3) paradigm-specific ethical and governance challenges, revealing divergent risks and mitigation strategies. Our analysis reveals that the choice of paradigm is strategic: symbolic systems dominate safety-critical domains (e.g., healthcare), while neural systems prevail in adaptive, data-rich environments (e.g., finance). Furthermore, we identify critical research gaps, including a significant deficit in governance models for symbolic systems and a pressing need for hybrid neuro-symbolic architectures. The findings culminate in a strategic roadmap arguing that the future of Agentic AI lies not in the dominance of one paradigm, but in their intentional integration to create systems that are both adaptable and reliable . This work provides the essential conceptual toolkit to guide future research, development, and policy toward robust and trustworthy hybrid intelligent systems.

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Publication Details

Journal
Artificial Intelligence Review
Published
2025-11-14
DOI
https://doi.org/10.1007/s10462-025-11422-4
Citations
11
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
7.20
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article

Agentic AI: a comprehensive survey of architectures, applications, and future directions

Mohamad Abou Ali, Jinan Charafeddine, Fadi Dornaika
11 citations
Artificial Intelligence Review
Artificial Intelligence in Healthcare and Education
7.20
article

Agentic AI: a comprehensive survey of architectures, applications, and future directions

Mohamad Abou Ali, Jinan Charafeddine, Fadi Dornaika
article en
11 citations

Abstract

Abstract Agentic AI represents a transformative shift in artificial intelligence, but its rapid advancement has led to a fragmented understanding, often conflating modern neural systems with outdated symbolic models—a practice known as conceptual retrofitting . This survey cuts through this confusion by introducing a novel dual-paradigm framework that categorizes agentic systems into two distinct lineages: the symbolic/classical (relying on algorithmic planning and persistent state) and the neural/generative (leveraging stochastic generation and prompt-driven orchestration). Through a systematic PRISMA-based review of 90 studies (2018–2025), we provide a comprehensive analysis structured around this framework across three dimensions: (1) the theoretical foundations and architectural principles defining each paradigm; (2) domain-specific implementations in healthcare, finance, and robotics, demonstrating how application constraints dictate paradigm selection; and (3) paradigm-specific ethical and governance challenges, revealing divergent risks and mitigation strategies. Our analysis reveals that the choice of paradigm is strategic: symbolic systems dominate safety-critical domains (e.g., healthcare), while neural systems prevail in adaptive, data-rich environments (e.g., finance). Furthermore, we identify critical research gaps, including a significant deficit in governance models for symbolic systems and a pressing need for hybrid neuro-symbolic architectures. The findings culminate in a strategic roadmap arguing that the future of Agentic AI lies not in the dominance of one paradigm, but in their intentional integration to create systems that are both adaptable and reliable . This work provides the essential conceptual toolkit to guide future research, development, and policy toward robust and trustworthy hybrid intelligent systems.

Artificial Intelligence ReviewVol. 59(1)
Ikerbasque (ES), University of the Basque Country (ES), International University of Beirut (LB), Vinci (France) (FR), Lebanese International University (LB)
Openalex Percentile: Top 3%
Artificial Intelligence in Healthcare and Education
7.20
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