Multi-Dimensional Characterization of Programmed Cell Death Patterns for Prognostic Stratification and Therapeutic Insights in Sepsis
This study delineates the multi-dimensional role of PCD in sepsis, establishes a reliable prognostic model with strong predictive value, and highlights SMYAD as a potential multi-target therapy. These findings provide new avenues for risk stratification and suggest the promise of integrating PCD biology with adjunctive immunomodulatory strategies.
Authors
- Zhou Chen (ORCID: https://orcid.org/0000-0001-5398-4654)
- Yunmeng Bai (ORCID: https://orcid.org/0000-0001-7915-4501)
Institutions
- Sun Yat-sen University (CN)
- Southern University of Science and Technology (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- ImmunoTargets and Therapy
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/itt.s555950
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00