Risk Factors for Sarcopenia in Women with Type 2 Diabetes and the Effects of Metformin: A Cross-Sectional Study of 7,731 Patients from the UK Biobank
Metformin use was cross-sectionally associated with higher odds of sarcopenia, particularly in older women with low physical activity and comorbidities. These findings highlight the need for further longitudinal and mechanistic studies to confirm the relationship and explore potential underlying mechanisms.
Authors
- Tongzhou Liang (ORCID: https://orcid.org/0000-0001-5920-5412)
- Wenjie Gao (ORCID: https://orcid.org/0000-0001-9456-8884)
- Huihong Shi (ORCID: https://orcid.org/0009-0002-8910-3307)
- Youxi Lin
- Zaoqiang Zhang
- Wenjun Hu (ORCID: https://orcid.org/0000-0001-8563-8844)
- Song Liu (ORCID: https://orcid.org/0000-0001-6166-4669)
- Jianan Chen (ORCID: https://orcid.org/0000-0002-6673-6884)
- Yanbo Chen (ORCID: https://orcid.org/0000-0002-5163-6506)
- Peijie Shi
- Nianchun Liao
- Xianjian Qiu
Institutions
- Sun Yat-sen University (CN)
- Chinese University of Hong Kong (HK)
- Sun Yat-sen Memorial Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2025-11-01
- DOI
- https://doi.org/10.2147/ijwh.s556435
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province