Tumor recurrence risk following different COS regimens in infertile women with borderline ovarian tumors: impact on IVF outcomes
E<sub>2</sub> on trigger day and the total dose of Gn are independent factors affecting the tumor-related outcome. Overstimulation of the ovaries should be avoided. Mild stimulation regimens and agonist/antagonist cycle regimens are both safe and effective for treating infertile patients with BOTs. Mild stimulation is more suitable and safer for patients with high-risk factors such as recurrence prior to COS and a serous histopathology with a micropapillary architecture.
Authors
- Jie Yan (ORCID: https://orcid.org/0000-0002-5138-5655)
- Xueling Song (ORCID: https://orcid.org/0000-0002-2287-6711)
- Yuan Li (ORCID: https://orcid.org/0000-0001-9004-5146)
- Xiumei Zhen (ORCID: https://orcid.org/0000-0001-5406-426X)
- Rong Li
- Liang Liang (ORCID: https://orcid.org/0000-0002-2444-4103)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s13048-025-01819-8
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China