The efficacy and safety of mirvetuximab soravtansine for the treatment of recurrent ovarian cancer: an update systematic review and meta-analysis

MIRV demonstrates significant efficacy and an acceptable safety profile in the treatment of recurrent ovarian cancer. Its use in platinum-resistant ovarian cancer with high FRα expression represents a particularly promising Therapeutic approach. Furthermore, the combination of MIRV and bevacizumab shows substantial potential for improving outcomes in patients with platinum-resistant disease.

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Publication Details

Journal
Discover Oncology
Published
2025-11-12
DOI
https://doi.org/10.1007/s12672-025-03933-x
Citations
2
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
3.40
Controls
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article

The efficacy and safety of mirvetuximab soravtansine for the treatment of recurrent ovarian cancer: an update systematic review and meta-analysis

Qiling Dai, Ting Du, Qin Huang, Jing Tang
2 citations
Discover Oncology
Ovarian cancer diagnosis and treatment
3.40
article

The efficacy and safety of mirvetuximab soravtansine for the treatment of recurrent ovarian cancer: an update systematic review and meta-analysis

Qiling Dai, Ting Du, Qin Huang, Jing Tang
article en
2 citations

Abstract

MIRV demonstrates significant efficacy and an acceptable safety profile in the treatment of recurrent ovarian cancer. Its use in platinum-resistant ovarian cancer with high FRα expression represents a particularly promising Therapeutic approach. Furthermore, the combination of MIRV and bevacizumab shows substantial potential for improving outcomes in patients with platinum-resistant disease.

Discover OncologyVol. 16(1)
Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Openalex Percentile: Top 7%
Ovarian cancer diagnosis and treatment
3.40
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