The efficacy and safety of mirvetuximab soravtansine for the treatment of recurrent ovarian cancer: an update systematic review and meta-analysis
MIRV demonstrates significant efficacy and an acceptable safety profile in the treatment of recurrent ovarian cancer. Its use in platinum-resistant ovarian cancer with high FRα expression represents a particularly promising Therapeutic approach. Furthermore, the combination of MIRV and bevacizumab shows substantial potential for improving outcomes in patients with platinum-resistant disease.
Authors
- Qiling Dai
- Ting Du (ORCID: https://orcid.org/0000-0002-9020-3746)
- Qin Huang (ORCID: https://orcid.org/0009-0001-7245-7996)
- Jing Tang (ORCID: https://orcid.org/0000-0002-8961-138X)
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1007/s12672-025-03933-x
- Citations
- 2
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.40