Age-stratified analysis of euploidy rates in Progestin-Primed Ovarian Stimulation (PPOS) utilizing micronized progesterone or dydrogesterone versus GnRH analogues
PPOS protocols using micronized progesterone or dydrogesterone were statistically comparable with conventional COS regimens in euploidy rates across all different age groups. Considering the significant impact of age, the necessity of refined age stratification for a more rigorous discussion about the aneuploidy risk of different COS protocols was emphasized.
Authors
- Xiaoting Diao
- Sheng Zhuang (ORCID: https://orcid.org/0000-0002-3172-1578)
- Haitao Zeng (ORCID: https://orcid.org/0000-0002-4843-4428)
- Rang Liu (ORCID: https://orcid.org/0000-0001-7151-7224)
- Xinyi Pan (ORCID: https://orcid.org/0000-0003-3357-5997)
- Yutong Wang (ORCID: https://orcid.org/0000-0003-3857-1821)
- Xiaoyan Liang (ORCID: https://orcid.org/0000-0002-4572-8754)
- Cong Fang (ORCID: https://orcid.org/0000-0001-9352-9525)
- Rui Xiang
Institutions
- Guangdong University of Technology (CN)
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s13048-025-01834-9
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sun Yat-sen University
- National Key Research and Development Program of China