Added value of sodium MRI in multiparametric MRI for WHO grade II astrocytoma surveillance during “watchful waiting”: initial experience
Elevation of rrCBV and rrCBF in the tumor indicates poor prognosis, in line with the literature. <sup>23</sup>Na-MRI can be used for WHO grade II astrocytoma surveillance. In some treatment-naïve WHO grade II astrocytomas, an initially high sodium signal seems to be prognostically favorable, contrary to the literature on <sup>23</sup>Na-MRI in postoperative aftercare. However, due to the small cohort size with evaluable <sup>23</sup>Na-MRI at baseline, evidence is limited. In future, <sup>23</sup>Na-MRI may help selecting patients for a "watchful waiting" strategy.
Authors
- Lars Gerigk
- Michael Weber (ORCID: https://orcid.org/0000-0002-8507-2219)
- Ioan N. Gemescu
- Sönke Langner (ORCID: https://orcid.org/0000-0001-7241-1173)
- Armin Michael Nagel (ORCID: https://orcid.org/0000-0003-0948-1421)
- Marco Essig (ORCID: https://orcid.org/0000-0002-7964-2297)
- Daniel Cantré (ORCID: https://orcid.org/0000-0003-1685-9744)
Institutions
- German Cancer Research Center (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Heidelberg University (DE)
- Universitätsklinikum Erlangen (DE)
- Research Centre of Medical Technology and Biotechnology (DE)
- University of Manitoba (CA)
- University of Rostock (DE)
Publication Details
- Journal
- Die Radiologie
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1007/s00117-025-01531-0
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bracco Imaging