Molecular abnormalities and clinical features in adult patients with acute myeloid leukemia in Thailand

The complexity of AML was influenced by various cytogenetic and molecular abnormalities, which contributed to patients' heterogeneous presentation and survival outcomes. In addition to the previous data, IDH1, IDH2, and DNMT3A mutations might have affected survival outcomes in AML patients in our retrospective cohort. However, further studies with larger sample sizes are needed to validate these observations.

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Publication Details

Journal
Diagnostic Pathology
Published
2025-11-12
DOI
https://doi.org/10.1186/s13000-025-01725-z
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00

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Molecular abnormalities and clinical features in adult patients with acute myeloid leukemia in Thailand

Suporn Chuncharunee, Pornnapa Police, Tichayapa Phojanasenee, Lalida Arsa et al.
Diagnostic Pathology
Acute Myeloid Leukemia Research
article

Molecular abnormalities and clinical features in adult patients with acute myeloid leukemia in Thailand

Suporn Chuncharunee, Pornnapa Police, Tichayapa Phojanasenee, Lalida Arsa, Pichika Chantrathammachart, Pimjai Niparuck, Phichchapha Noikongdee, Artit Jinawath, Teeraya Puavilai, Pakatorn Sae-Lim, Thanakrit Piyajaroenkij, Phatsorn Choksomnuk
article en

Abstract

The complexity of AML was influenced by various cytogenetic and molecular abnormalities, which contributed to patients' heterogeneous presentation and survival outcomes. In addition to the previous data, IDH1, IDH2, and DNMT3A mutations might have affected survival outcomes in AML patients in our retrospective cohort. However, further studies with larger sample sizes are needed to validate these observations.

Diagnostic PathologyVol. 20(1)
Mahidol University (TH), Ramathibodi Hospital (TH)
Mahidol University
Openalex Percentile: Top 55%
Acute Myeloid Leukemia Research
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Molecular abnormalities and clinical features in adult patients with acute myeloid leukemia in Thailand — Suporn Chuncharunee, Pornnapa Police, et al. · Diagnostic Pathology (2025) | TGRS Research Map | TGRS