Comparison of boiling versus magnetic bead techniques in nucleic acid extraction for human papillomavirus detection: evidence based 17,179 cases
Compared to the boiling method, the magnetic bead-based nucleic acid extraction technique exhibited superior anti-interference capabilities and a significant higher detection rate for HPV. Furthermore, it is highly cost-effective. It is anticipated that the magnetic bead method will be fully adopted for HPV detection in place of the boiling method in the future. Of course, more research is needed to verify this conclusion.
Authors
- Guowei Liang
- Zhiyong Lv
- Yunxiang Li (ORCID: https://orcid.org/0000-0002-4019-7843)
- Qian Gao (ORCID: https://orcid.org/0009-0002-9974-1273)
- Jing Feng (ORCID: https://orcid.org/0000-0001-9805-0353)
- Mingjian Bai (ORCID: https://orcid.org/0009-0007-5659-9330)
- Frank H. Fu
- Fucun Ma
Institutions
- Peking University (CN)
- Aerospace Center Hospital (CN)
- Beijing Haidian Hospital (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s12985-025-02999-x
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Aerospace Center Hospital