Empyema as an Unusual Presentation of Lung Cancer

Malignant empyema is a rare presentation of lung cancer, marked by the accumulation of frank pus in the pleural space. It can result from various mechanisms, including direct tumor invasion, airway obstruction, immunosuppression, and secondary infections. The clinical presentation is often complex, with symptoms overlapping those of the underlying malignancy and potential complications like sepsis. In the present case, the patient initially presented with chest infection symptoms but, on further investigations, was diagnosed with lung malignancy. Treatment requires a multidisciplinary approach focused on draining the infected fluid, managing infection with antibiotics, and addressing the underlying cancer. Overall, the prognosis of malignant empyema is poor and often fatal.

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Publication Details

Journal
Cureus
Published
2025-11-12
DOI
https://doi.org/10.7759/cureus.96674
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Empyema as an Unusual Presentation of Lung Cancer

Anita Dhupar, Navneet Kaur, Kamran Amin, Ali Hussain et al.
Cureus
Pleural and Pulmonary Diseases
article

Empyema as an Unusual Presentation of Lung Cancer

Anita Dhupar, Navneet Kaur, Kamran Amin, Ali Hussain, Faisal Arslan, Joohi Khan
article en

Abstract

Malignant empyema is a rare presentation of lung cancer, marked by the accumulation of frank pus in the pleural space. It can result from various mechanisms, including direct tumor invasion, airway obstruction, immunosuppression, and secondary infections. The clinical presentation is often complex, with symptoms overlapping those of the underlying malignancy and potential complications like sepsis. In the present case, the patient initially presented with chest infection symptoms but, on further investigations, was diagnosed with lung malignancy. Treatment requires a multidisciplinary approach focused on draining the infected fluid, managing infection with antibiotics, and addressing the underlying cancer. Overall, the prognosis of malignant empyema is poor and often fatal.

CureusVol. 17(11)
Pinderfields Hospital (GB)
Openalex Percentile: Top 51%
Pleural and Pulmonary Diseases
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Empyema as an Unusual Presentation of Lung Cancer — Anita Dhupar, Navneet Kaur, et al. · Cureus (2025) | TGRS Research Map | TGRS