Brain-Derived Neurotrophic Factor Levels Are Associated With Depressive Symptoms in Patients With Asthma
Serum BDNF levels are positively associated with both depressive symptoms and asthma severity in patients with asthma. These findings suggest that the mechanisms underlying depressive symptoms in patients with asthma may differ from those in major depression, particularly with respect to the role of BDNF.
Authors
- Toshihito Otani
- Takeshi Isobe (ORCID: https://orcid.org/0000-0002-3498-9772)
- Noboru Hattori (ORCID: https://orcid.org/0000-0002-8234-942X)
- Tsunahiko Hirano (ORCID: https://orcid.org/0000-0002-5475-0806)
- Hiroshi Iwamoto (ORCID: https://orcid.org/0000-0003-4922-5334)
- Naoko Higaki
- Akihito Yokoyama (ORCID: https://orcid.org/0000-0002-1451-1210)
- Mayuka Yamane (ORCID: https://orcid.org/0000-0001-8693-3220)
- Kazuto Matsunaga (ORCID: https://orcid.org/0000-0002-0514-3241)
- Ayumi Fukatsu-Chikumoto
- Kazuma Kawamoto
- Yoshihiro Amano
Institutions
- Hiroshima University (JP)
- Shimane University (JP)
- Yamaguchi University (JP)
- University of Kochi (JP)
- Kochi Medical School Hospital (JP)
- Kōchi University (JP)
Publication Details
- Journal
- The Journal of Allergy and Clinical Immunology In Practice
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.jaip.2025.11.001
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00