Longitudinal dysbiosis of gut bacteriome and mycobiome in patients with severe acute pancreatitis and its association with mortality
Our study provided a comprehensive profile of gut bacteriome and mycobiome in SAP patients and identified the temporal trajectory alterations of microbiome associated with mortality. These findings underscore the importance of early recognition of pathobiome states and the potential role for the modulation of microbiota during the development of SAP.
Authors
- Liang Xia (ORCID: https://orcid.org/0000-0001-7209-9407)
- Yi Hu (ORCID: https://orcid.org/0000-0003-2708-7612)
- Xueyang Li (ORCID: https://orcid.org/0000-0002-7806-5811)
- Xin Huang (ORCID: https://orcid.org/0000-0002-4874-3626)
- Cong He (ORCID: https://orcid.org/0000-0002-1185-5456)
- Nonghua Lü (ORCID: https://orcid.org/0000-0003-4373-551X)
- Yin Zhu (ORCID: https://orcid.org/0000-0002-7561-2306)
- Ling Ding (ORCID: https://orcid.org/0009-0005-8189-2040)
- Jinyun Wang (ORCID: https://orcid.org/0009-0003-8780-9979)
- Lingyu Luo
- Huifang Xiong
- Yupeng Lei
- Wenhua He (ORCID: https://orcid.org/0000-0001-5499-1346)
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s12866-025-04467-6
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Nanchang University
- Recruitment Program of Global Experts