Biochemical and histopathological investigation to study the impact of pyriproxyfen exposure on ovarian morphology and reproductive function in female rats
Oral administration of PYR in adult female rats leads to altered organ weights, disturbed normal estrous cycle, increased triglycerides and total cholesterol, reduced high-density lipids concentrations, and damaged ovarian architecture, affecting biochemical and reproductive function in female rats.
Authors
- Houda Amor (ORCID: https://orcid.org/0000-0003-1442-8836)
- Mehwish David (ORCID: https://orcid.org/0000-0002-5160-2728)
- Dara Al Disi
- Sajid Ali (ORCID: https://orcid.org/0000-0002-0696-3057)
- Fohad Mabood Husain (ORCID: https://orcid.org/0000-0001-6598-4328)
- Sarwat Jahan (ORCID: https://orcid.org/0000-0001-8363-4196)
- Suhail Razak (ORCID: https://orcid.org/0000-0003-2167-8630)
- Hina Afaqi
- J. Fatima
- Tayyaba Afsar (ORCID: https://orcid.org/0000-0003-3181-5731)
Institutions
- Quaid-i-Azam University (PK)
- University of Freiburg (DE)
- King Saud bin Abdulaziz University for Health Sciences (SA)
- King Saud Medical City (SA)
- University Medical Center Freiburg (DE)
- King Saud University (SA)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s40360-025-01045-4
- Citations
- 1
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- King Saud University