Hyperuricemia and Cardiovascular Disease: Mechanisms, Associations, and Therapeutic Implications – A Literature Review
Uric acid has emerged as a potential biomarker for cardiovascular risk. Hyperuricemia, described as an abnormally elevated concentration of uric acid in the bloodstream, has been associated with the development of cardiovascular diseases such as hypertension, atrial fibrillation, heart failure, and coronary heart disease. Recent studies have investigated the potential benefits of using uric acid-lowering therapy in slowing the progression of these diseases. In this review, we summarize current evidence on the impact of hyperuricemia on cardiovascular diseases and the effectiveness of urate-lowering therapy in affected patients.
Authors
- Weronika Kalinowska (ORCID: https://orcid.org/0009-0005-4630-467X)
- Anna Szeliga (ORCID: https://orcid.org/0009-0006-1832-5569)
- Matthias Borowski (ORCID: https://orcid.org/0009-0001-0789-804X)
- Tomasz Karol Książek (ORCID: https://orcid.org/0009-0000-9852-1434)
- K Kozłowska (ORCID: https://orcid.org/0009-0008-6541-207X)
- Anna Ewelina Francuziak (ORCID: https://orcid.org/0009-0005-9810-7758)
- Paulina Sara Kulasza (ORCID: https://orcid.org/0009-0003-5829-6721)
- Michał Szczepański (ORCID: https://orcid.org/0009-0002-4828-6709)
- Natalia Dzieszko (ORCID: https://orcid.org/0009-0008-8743-6590)
- Piotr Mikołaj Dembicki (ORCID: https://orcid.org/0009-0005-0709-9220)
Institutions
- Medical University of Warsaw (PL)
- University Clinical Hospital In Bialystok (PL)
- University Hospital (CA)
- John Paul II Hospital (PL)
- State Higher Vocational School in Krosno (PL)
- Krakow Cardiovascular Research Institute (PL)
- Wojewódzki Szpital Zespolony im. Jędrzeja Śniadeckiego (PL)
- Children's Specialized Hospital (US)
Publication Details
- Journal
- Quality in Sport
- Published
- 2025-11-12
- DOI
- https://doi.org/10.12775/qs.2025.45.66515
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00