Dapagliflozin Mitigates Medullary Hypoxia in CKD Patients

These findings suggest that dapagliflozin may mitigate medullary hypoxia in CKD patients. BOLD-MRI could serve as a valuable biomarker for assessing renal functional reserve and predicting CKD progression. Further studies are warranted to confirm these effects and explore underlying molecular mechanisms.

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Publication Details

Journal
Kidney360
Published
2025-11-12
DOI
https://doi.org/10.34067/kid.0000001015
Citations
1
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.43
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article

Dapagliflozin Mitigates Medullary Hypoxia in CKD Patients

Giacomo Garibotto, Emilio Venturelli, Pasquale B. Esposito, Francesca Cappadona et al.
1 citations
Kidney360
Parathyroid Disorders and Treatments
1.43
article

Dapagliflozin Mitigates Medullary Hypoxia in CKD Patients

Giacomo Garibotto, Emilio Venturelli, Pasquale B. Esposito, Francesca Cappadona, Francesca Viazzi, Lucia Macciò, Maria Beatrice Damasio, Elisa Russo, Giulio Ferrazzi, R Grillo, Julie Di Vincenzo
article en
1 citations

Abstract

These findings suggest that dapagliflozin may mitigate medullary hypoxia in CKD patients. BOLD-MRI could serve as a valuable biomarker for assessing renal functional reserve and predicting CKD progression. Further studies are warranted to confirm these effects and explore underlying molecular mechanisms.

Kidney360Vol. 7(3)
Istituto Giannina Gaslini (IT), Ospedale Policlinico San Martino (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Philips (Italy) (IT), University of Genoa (IT)
Openalex Percentile: Top 14%
Parathyroid Disorders and Treatments
1.43
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Dapagliflozin Mitigates Medullary Hypoxia in CKD Patients — Giacomo Garibotto, Emilio Venturelli, et al. · Kidney360 (2025) | TGRS Research Map | TGRS