Seven‐probe fiber detector for time‐resolved source tracking in HDR‐brachytherapy: Pre‐clinical experimental evaluation
A 7SD based on <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow><mml:msub><mml:mi>Gd</mml:mi> <mml:mn>2</mml:mn></mml:msub> <mml:msub><mml:mi>O</mml:mi> <mml:mn>2</mml:mn></mml:msub> <mml:mtext>S:Tb</mml:mtext></mml:mrow> <mml:annotation>${\rm Gd}_2{\rm O}_2\text{S:Tb}$</mml:annotation></mml:semantics> </mml:math> , coupled with an sCMOS camera, demonstrates its suitability for time-resolved IVD in monitoring HDR-BT treatments. The 7SD substantially extends the monitoring volume along both the source's axial path and the orthogonal radial direction, enabling accurate source tracking across treatment geometries representative of a wide variety of HDR-BT procedures. By detecting subtle afterloader malfunctions, the 7SD offers a precise and valuable means of evaluating the integrity of HDR-BT setups and procedures. Its high-resolution monitoring capabilities, confirmed biocompatibility, scalability, and compatibility with standard BT needles, catheters, and applicators underscore its potential for clinical implementation.
Authors
- Karine Charrière (ORCID: https://orcid.org/0000-0003-4542-8003)
- Julien Crouzilles
- Gwenaël Rolin (ORCID: https://orcid.org/0000-0002-6234-869X)
- Thierry Grosjean (ORCID: https://orcid.org/0000-0002-9470-7693)
- Lionel Pazart
- Léone Aubignac
- J.F. Vinchant
- Thomas Lihoreau (ORCID: https://orcid.org/0000-0001-8417-6609)
- Samir Laskri
- Mathieu Gonod
- Miguel Angel Suárez
- Emmanuel Dordor
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Centre Georges François Leclerc (FR)
- Université Marie et Louis Pasteur (FR)
- Université de Franche-Comté (FR)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/mp.70080
- Primary Topic
- Photoacoustic and Ultrasonic Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00