Clinicopathologic and Molecular Characteristics of High-Grade Appendiceal Mucinous Neoplasms
This is the largest cohort of patients with HAMN characterized to date. HAMNs are associated with more frequent and higher-grade PD than are LAMNs. The presence and type of PD influence both RFS and OS for patients with AMN. Overall, there is a trend towards decreased RFS in patients with HAMN than with LAMN, but OS was similar.
Authors
- Michael J. Overman (ORCID: https://orcid.org/0000-0001-5377-135X)
- Melissa W. Taggart (ORCID: https://orcid.org/0000-0002-7803-9904)
- John Paul Shen (ORCID: https://orcid.org/0000-0003-4588-2775)
- Wai Chin Foo (ORCID: https://orcid.org/0000-0002-0471-4911)
- Christopher P. Scally
- Keith F. Fournier (ORCID: https://orcid.org/0000-0002-7882-9826)
- Michael G. White (ORCID: https://orcid.org/0000-0001-5022-5505)
- Yun Song (ORCID: https://orcid.org/0000-0001-6670-3807)
- Mark J. Routbort (ORCID: https://orcid.org/0000-0003-4860-261X)
- J. Bryan Iorgulescu (ORCID: https://orcid.org/0000-0003-1405-3667)
- Beth A. Helmink (ORCID: https://orcid.org/0000-0002-8206-0351)
- Ashlee Seldomridge (ORCID: https://orcid.org/0000-0001-9635-5006)
- Sun Mi Lee (ORCID: https://orcid.org/0009-0006-9516-1780)
- Richard E. Royal
- Paul F. Mansfield
Institutions
- Maine Medical Center (US)
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1245/s10434-025-18672-0
- Citations
- 1
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 2.01