Laser Photobiomodulation of Human Dermal Fibroblasts Combined With Plasma Rich in Growth Factors and Platelet‐Rich Plasma: A Comparative In Vitro Analysis
PRP and PRGF synergistically enhanced fibroblast proliferation and metabolism when combined with LLLT. PRGF consistently demonstrated greater effects compared with PRP. Optimal stimulation was achieved with 90 s of LLLT at 10 mW (3.78 J/cm<sup>2</sup>) combined with 30% PRP or 60% PRGF.
Authors
- Mohammad Ali Nilforoshzadeh
- Manijhe Mokhtari‐Dizaji (ORCID: https://orcid.org/0000-0003-1598-2038)
- Zeinab Hormozi‐Moghaddam (ORCID: https://orcid.org/0000-0001-9345-5706)
- Mohsen Bakhshandeh (ORCID: https://orcid.org/0000-0002-6546-7483)
- Syahril Abdullah (ORCID: https://orcid.org/0000-0003-2718-6266)
Institutions
- Tarbiat Modares University (IR)
- Iran University of Medical Sciences (IR)
- University of Tehran (IR)
- Stem Cell Technology Research Center (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Photodermatology Photoimmunology & Photomedicine
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1111/phpp.70063
- Citations
- 1
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 1.36