Efficacy and safety of atezolizumab compared to docetaxel in non-small cell lung cancer patients regardless of PD-L1 status: a systematic review and meta-analysis

Atezolizumab showed OS improvement and great safety in NSCLC. There was no direct relationship between the effectiveness of atezolizumab and PD-L1 expression status. The safety and maintenance of efficacy remain undetermined, and further research is needed to explore the long-term effectiveness of atezolizumab.

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Publication Details

Journal
Chinese Clinical Oncology
Published
2025-10-01
DOI
https://doi.org/10.21037/cco-25-45
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of atezolizumab compared to docetaxel in non-small cell lung cancer patients regardless of PD-L1 status: a systematic review and meta-analysis

Yonghong Cui, Hai Zhao, Ximing Li
Chinese Clinical Oncology
Cancer Immunotherapy and Biomarkers
article

Efficacy and safety of atezolizumab compared to docetaxel in non-small cell lung cancer patients regardless of PD-L1 status: a systematic review and meta-analysis

Yonghong Cui, Hai Zhao, Ximing Li
article en

Abstract

Atezolizumab showed OS improvement and great safety in NSCLC. There was no direct relationship between the effectiveness of atezolizumab and PD-L1 expression status. The safety and maintenance of efficacy remain undetermined, and further research is needed to explore the long-term effectiveness of atezolizumab.

Chinese Clinical OncologyVol. 14(5)
China National Pharmaceutical Group Corporation (China) (CN)
Openalex Percentile: Top 53%
Cancer Immunotherapy and Biomarkers
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