Does Covid-19 Cause Avascular Necrosis?

COVID-19 has been associated with an increased risk of avascular necrosis (AVN), which affects various joints, including the hip, vertebrae, knee, and jaw. Understanding AVN's pathogenesis and risk factors as a consequence of COVID-19 is essential for improving treatment and identifying preventive measures. This retrospective cohort study aims to assess the impact of COVID-19 on the etiology of AVN and raise awareness among clinicians. The study analyzed patients diagnosed with AVN and treated with Hyperbaric Oxygen Therapy at Gülhane Training and Research Hospital from January 2018 to January 2023. Patients were categorized into two groups: those admitted before the pandemic (the control group) and those admitted after (the study group). The results showed a significant increase in AVN cases during the post-pandemic period, with a higher incidence of femoral head involvement and more advanced stages of AVN in patients with a history of COVID-19. The findings suggest that COVID-19 and high-dose steroid use may increase AVN risk, highlighting the need for careful steroid management and monitoring for joint pain in these patients. Further research is recommended to explore the link between COVID-19 and AVN, the duration of symptoms, and the prognostic implications.

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PubMed
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2025-11-12
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Bone and Joint Diseases
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article

Does Covid-19 Cause Avascular Necrosis?

Kübra Özgök Kangal, Burak Turgut, Esat Artan, Kübra Canarslan-Demir
PubMed
Bone and Joint Diseases
article

Does Covid-19 Cause Avascular Necrosis?

Kübra Özgök Kangal, Burak Turgut, Esat Artan, Kübra Canarslan-Demir
article en

Abstract

COVID-19 has been associated with an increased risk of avascular necrosis (AVN), which affects various joints, including the hip, vertebrae, knee, and jaw. Understanding AVN's pathogenesis and risk factors as a consequence of COVID-19 is essential for improving treatment and identifying preventive measures. This retrospective cohort study aims to assess the impact of COVID-19 on the etiology of AVN and raise awareness among clinicians. The study analyzed patients diagnosed with AVN and treated with Hyperbaric Oxygen Therapy at Gülhane Training and Research Hospital from January 2018 to January 2023. Patients were categorized into two groups: those admitted before the pandemic (the control group) and those admitted after (the study group). The results showed a significant increase in AVN cases during the post-pandemic period, with a higher incidence of femoral head involvement and more advanced stages of AVN in patients with a history of COVID-19. The findings suggest that COVID-19 and high-dose steroid use may increase AVN risk, highlighting the need for careful steroid management and monitoring for joint pain in these patients. Further research is recommended to explore the link between COVID-19 and AVN, the duration of symptoms, and the prognostic implications.

PubMedVol. 52(3)
Gülhane Askerî Tıp Akademisi (TR), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Openalex Percentile: Top 56%
Bone and Joint Diseases
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Does Covid-19 Cause Avascular Necrosis? — Kübra Özgök Kangal, Burak Turgut, et al. · PubMed (2025) | TGRS Research Map | TGRS