Physical compatibility of omadacycline with intravenous agents used in the treatment of <i>Mycobacteroides abscessus</i> pulmonary disease

At clinical concentrations of agents used in the treatment of pulmonary M. abscessus disease, omadacycline appears to be physically compatible in dual-agent combinations in Y-site infusion with amikacin, azithromycin, cefoxitin, imipenem/cilastatin, and linezolid, as well as in triple combinations of omadacycline plus imipenem/cilastatin and amikacin and omadacycline plus linezolid and amikacin.