Neuroimaging epicenters and the related neurobiological signatures in patients with postherpetic neuralgia
we used a novel method to identify the ventroanterior thalamus as the potential epicenter of PHN, supported by the neurobiological interpretations. The presence of epicenters highlights that there may exist a reliable neuroimaging biomarker, which offers potential treatment targets.
Authors
- Xinwei Luo (ORCID: https://orcid.org/0000-0003-1165-1522)
- Jiaxiang Xiong
- Minmin Lu (ORCID: https://orcid.org/0000-0002-7210-4170)
- Qi Han (ORCID: https://orcid.org/0000-0002-1107-3286)
- Yun Wang (ORCID: https://orcid.org/0000-0002-2648-4467)
- Zhian Hu (ORCID: https://orcid.org/0000-0002-4439-537X)
- He Xie (ORCID: https://orcid.org/0000-0003-3687-7886)
- Xiaoke Luo (ORCID: https://orcid.org/0009-0006-8028-3822)
- Li Li (ORCID: https://orcid.org/0000-0002-2698-3434)
- Xiaolong Zhang (ORCID: https://orcid.org/0000-0003-3955-736X)
- Xiao Wang (ORCID: https://orcid.org/0000-0002-0077-7341)
- Qin Li (ORCID: https://orcid.org/0000-0003-1229-9698)
- Chao He (ORCID: https://orcid.org/0009-0005-2552-5000)
- Yong Liu (ORCID: https://orcid.org/0000-0002-8311-258X)
- Shiyin Li (ORCID: https://orcid.org/0000-0002-1550-4258)
- Yuanjing Zhang (ORCID: https://orcid.org/0000-0002-1496-5490)
- Jiafei Chen (ORCID: https://orcid.org/0009-0001-5106-4990)
- Qin Xiao (ORCID: https://orcid.org/0000-0002-0051-9924)
- Jie Yan (ORCID: https://orcid.org/0000-0003-2939-5395)
- Haolei Bai
- Wei Yang (ORCID: https://orcid.org/0009-0005-8713-6262)
Institutions
- Army Medical University (CN)
- Peking University (CN)
- Hainan University (CN)
- Xinqiao Hospital (CN)
- Southwest Hospital (CN)
- Hainan Agricultural School (CN)
- State Key Laboratory of Natural and Biomimetic Drugs (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1186/s10194-025-02204-y
- Primary Topic
- Trigeminal Neuralgia and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China