Natural compounds targeting mitochondrial metabolism in cancer therapy: a literature review
Natural compounds can act in different pathways of mitochondrial metabolism to exert their antitumoral effects, however, some limitations need to be overcome. Developing natural product-based hybrids through the conjugation of natural compounds with bioactive molecules has gained interest to surpass these limitations, representing a good strategy to enhance the anticancer treatment effectiveness of natural products.
Authors
- Janaína Fernandes (ORCID: https://orcid.org/0000-0002-3442-6101)
- Grazielle Silva Paz
Institutions
- Universidade Federal do Rio de Janeiro (BR)
Publication Details
- Journal
- Chinese Clinical Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/cco-25-51
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00