Extracorporeal shockwave therapy ameliorates skin inflammation of imiquimod-induced psoriasis in mice
ESWT significantly reduced epidermal thickness, macrophage and IL-17<sup>+</sup> cell infiltration, and the expression of IL-23 and TNF-α in IMQ-induced psoriasis mice. These findings suggest that ESWT may ameliorate psoriatic skin lesions by modulating macrophage activity and IL-17<sup>+</sup> cell-mediated inflammation.
Authors
- Chang‐Chun Hsiao (ORCID: https://orcid.org/0000-0002-7275-4675)
- Shang‐Hung Lin (ORCID: https://orcid.org/0000-0002-7069-6993)
- Chih‐Hung Lee (ORCID: https://orcid.org/0000-0001-9804-3874)
- P.‐J. Cheng
Institutions
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Biomedical Journal
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.bj.2025.100930
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00