Cardiomyopathy Associated with Subclinical Becker Muscular Dystrophy in a Patient Presenting with Anesthesia-induced Rhabdomyolysis
Becker muscular dystrophy (BMD)-associated cardiomyopathy may be overlooked in patients with dilated cardiomyopathy (DCM). We herein report a case of cardiomyopathy related to BMD in which anesthesia-induced rhabdomyolysis led to a diagnosis of BMD. The patient experienced anesthesia-induced rhabdomyolysis during cardiac resynchronization therapy. The patient became inotrope-dependent, and a left ventricular assist device was safely implanted by considering the use of anesthetic agents to avoid rhabdomyolysis. The abnormal immunohistochemical staining pattern of dystrophin protein in the myocardium and dystrophin gene mutation confirmed the diagnosis of BMD. BMD should thus be considered in patients with DCM to prevent perioperative complications including rhabdomyolysis.
Authors
- Yoshihiko Ikeda
- Kento Kumai
- Osamu Seguchi (ORCID: https://orcid.org/0000-0003-0820-9629)
- Gaku Narita
- Chisato Ôta
- Yasumasa Tsukamoto (ORCID: https://orcid.org/0000-0002-0963-6940)
- Satsuki Fukushima (ORCID: https://orcid.org/0000-0002-9481-8860)
- Kinta Hatakeyama (ORCID: https://orcid.org/0000-0001-7729-1836)
- Reiko Shiomura (ORCID: https://orcid.org/0000-0002-9755-0679)
- Makoto Araki (ORCID: https://orcid.org/0000-0002-1540-9672)
- Hirotaka Kawauchi
- Keiko Ohta‐Ogo
- Naomasa Makita (ORCID: https://orcid.org/0000-0002-1807-672X)
- Taisuke Ishikawa (ORCID: https://orcid.org/0000-0001-8195-4700)
- Katsuki Nagatomo
- Takuya Watanabe (ORCID: https://orcid.org/0000-0002-9166-1749)
- Hiroki Mochizuki
- Takuma Sato (ORCID: https://orcid.org/0000-0003-4161-4052)
- T. Iwanaga
Institutions
- Obayashi (Japan) (JP)
- National Cerebral and Cardiovascular Center (JP)
- Kagoshima University Hospital (JP)
- Toujinkai Hospital (JP)
Publication Details
- Journal
- Internal Medicine
- Published
- 2025-11-12
- DOI
- https://doi.org/10.2169/internalmedicine.5972-25
- Citations
- 3
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Japan Society for the Promotion of Science