Delirium in Nonagenarians with Acute Coronary Syndrome Following Percutaneous Coronary Intervention
The aging population has led to an increase in nonagenarians undergoing percutaneous coronary intervention (PCI). Nonagenarian patients are at risk for geriatric complications, including delirium, which can worsen clinical outcomes. However, research on delirium and its clinical implications in nonagenarians with acute coronary syndrome (ACS) following PCI is limited.This retrospective observational cohort study analyzed data from 307 nonagenarians with ACS who underwent PCI. Delirium was diagnosed using the Diagnostic and Statistical Manual of Mental Disorders-5 criteria. Prevalence and prognostic impact of delirium during hospitalization were investigated.Delirium occurred in 85 patients (27.7%) during hospitalization. Patients with delirium had longer hospital stays and lower discharge rates to home or the same location as prior to hospitalization compared to patients without delirium. However, in-hospital mortality rates were comparable between the groups. Over a median follow-up of 480 days, no significant differences were found in all-cause mortality between the two groups.Delirium was common among nonagenarians with ACS following PCI. While delirium was associated with length of hospital stays and discharge destination, it was not linked to survival rates. Prevention, early detection, and effective management of delirium are important for optimizing care in super-aged patients following PCI.
Authors
- Yosuke Tatami
- Kenji Takemoto (ORCID: https://orcid.org/0000-0003-2119-2411)
- Masato Watarai
- Yukihiko Yoshida
- Naoki Yoshioka (ORCID: https://orcid.org/0000-0003-3700-9570)
- Kotaro Tokuda
- Teruhiro Sakaguchi
- Miho Tanaka (ORCID: https://orcid.org/0000-0003-4230-9391)
- Hideki Ishii (ORCID: https://orcid.org/0000-0003-4348-0123)
- Yosuke Negishi
- Itsuro Morishima (ORCID: https://orcid.org/0000-0002-1444-090X)
- Yusuke Uemura (ORCID: https://orcid.org/0000-0002-2262-1452)
- Hikaru Hayakawa
- Toshiyuki Noda (ORCID: https://orcid.org/0009-0002-3198-7648)
- Toshikazu Tanaka (ORCID: https://orcid.org/0000-0002-0711-7880)
- Ruka Yoshida (ORCID: https://orcid.org/0000-0002-1693-7389)
- Norio Umemoto (ORCID: https://orcid.org/0000-0002-0409-8610)
- Akihito Tanaka (ORCID: https://orcid.org/0000-0001-8866-5901)
- Makoto Iwama (ORCID: https://orcid.org/0000-0003-3806-5435)
- Naoki Shibata (ORCID: https://orcid.org/0000-0001-6748-1505)
- Hiroshi Asano (ORCID: https://orcid.org/0000-0002-5867-8899)
- Shogo Yamaguchi (ORCID: https://orcid.org/0009-0005-2171-6301)
- Hiroshi Tashiro
- Taiki Ohashi
- Yasunobu Takada
- Toyoaki Murohara
Institutions
- Gunma University (JP)
- Konan Kosei Hospital (JP)
- Ichinomiya Municipal City Hospital (JP)
- Okazaki City Hospital (JP)
- Ogaki Municipal Hospital (JP)
- Gifu Prefectural General Medical Center (JP)
- Toyota Kosei Hospital (JP)
- Anjo Kosei Hospital (JP)
- Japanese Red Cross Nagoya Daini Hospital (JP)
- Tosei General Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- International Heart Journal
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1536/ihj.25-289
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00