Impact of diabetes on the effects of SGLT2 inhibitors on kidney outcomes: An updated drug/dose-dependent meta-analysis

SGLT2 inhibitors confer renal protection in both diabetic and non-diabetic populations, supporting their use in CKD management across a broad spectrum of patients. However, careful drug selection is warranted in diabetic patients at risk for DKA.

Authors

Jingfeng Qian
Yanqiu Xu (ORCID: https://orcid.org/0000-0002-2201-4361)

Publication Details

Journal: Clinical Nephrology
Published: 2025-11-14
DOI: https://doi.org/10.5414/cn111749
Primary Topic: Diabetes Treatment and Management
Type: article
Field-Weighted Citation Impact: 0.00

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article

Impact of diabetes on the effects of SGLT2 inhibitors on kidney outcomes: An updated drug/dose-dependent meta-analysis

Jingfeng Qian, Yanqiu Xu

Nov 14, 2025

Clinical Nephrology

Diabetes Treatment and Management

article

Impact of diabetes on the effects of SGLT2 inhibitors on kidney outcomes: An updated drug/dose-dependent meta-analysis

Jingfeng Qian, Yanqiu Xu

November 14, 2025article en

Abstract

Clinical NephrologyVol. 105(2)

Openalex Percentile: Top 54%

Diabetes Treatment and Management

DOI Source OpenAlex

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Impact of diabetes on the effects of SGLT2 inhibitors on kidney outcomes: An updated drug/dose-dependent meta-analysis — Jingfeng Qian, Yanqiu Xu · Clinical Nephrology (2025) | TGRS Research Map | TGRS