Silica-coated natural iron ore particles for genomic DNA separation
As an alternative way to separation of biological molecules, silica coated magnetite ore particles were prepared through two step synthetic method including ball milling of iron ore powder followed by silica coating with Stöber method. As synthesized silica coated magnetic ore particles were composed mainly of magnetite and other accompanying minerals such as hematite and Al2O3, ZrO2. The particles were irregular in shape, with average size of 0.4 ± 0.3 µm as demonstrated with SEM. Field dependent magnetization showed that silica-coated magnetite ore particles are soft ferromagnet with coercivity of 320Oe and remanent magnetization of 2.26 emu/g. Using these particles, genomic DNA was successfully separated from E. coli with sufficient yield and purity comparable to those obtained with a commercial magnetic separation kit, demonstrating their potential for bioseparation from diverse biological sources.
Authors
- Sarangerel Oidovsambuu (ORCID: https://orcid.org/0000-0001-5062-7440)
- Enkhtsetseg Dashjav (ORCID: https://orcid.org/0000-0002-7823-7759)
- Ochirkhuyag Bayanjargal (ORCID: https://orcid.org/0000-0003-0640-3313)
- Tuul Tsagaantsooj (ORCID: https://orcid.org/0000-0003-2064-9205)
- Tsedev Ninjbadgar (ORCID: https://orcid.org/0000-0002-5725-3637)
- Odgerel Oidovsambuu (ORCID: https://orcid.org/0000-0001-6872-3385)
- Sansarmaa Sanchigdorj (ORCID: https://orcid.org/0009-0000-7433-4503)
- Ganzorig Chimed (ORCID: https://orcid.org/0009-0007-4042-6814)
Institutions
- Mongolian Academy of Sciences (MN)
- Mongolian University of Science and Technology (MN)
- Forschungszentrum Jülich (DE)
- Institute of Chemistry and Chemical Technology (MN)
- National University of Mongolia (MN)
Publication Details
- Journal
- Mongolian Journal of Chemistry
- Published
- 2025-11-13
- DOI
- https://doi.org/10.5564/mjc.v26i54.4144
- Primary Topic
- Iron oxide chemistry and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National University of Mongolia
- Mongolian Foundation for Science and Technology
- National Natural Science Foundation of China