Sarcopenia and Functional Decline in Postmenopausal Women: The Roles of Type 2 Diabetes and Physical Activity
Distinct associational profiles emerged for sarcopenia and functional decline in postmenopausal women. While T2DM and obesity are independently associated with sarcopenia through metabolic mechanisms, physical inactivity emerged as the strongest predictor of functional impairment. These findings support targeted interventions: metabolic optimization for muscle mass preservation and structured physical activity, particularly resistance training, for maintaining functional independence in this high-risk population.
Authors
- Paulo Adriano Schwingel (ORCID: https://orcid.org/0000-0002-2935-3403)
- Keyla Brandão Costa (ORCID: https://orcid.org/0000-0001-6797-7789)
- Lucas Savassi Figueiredo (ORCID: https://orcid.org/0000-0001-5853-4978)
- Maria João Carvalho (ORCID: https://orcid.org/0000-0001-9409-5466)
- Anthony Rodrigues de Vasconcelos (ORCID: https://orcid.org/0000-0001-6691-4436)
- Denise Maria Martins Vancea (ORCID: https://orcid.org/0000-0002-0590-8937)
- Manoel da Cunha Costa (ORCID: https://orcid.org/0000-0001-8815-8846)
- Pedro Weldes da Silva Cruz (ORCID: https://orcid.org/0000-0002-9890-8783)
- Aline de Freitas Brito (ORCID: https://orcid.org/0000-0002-0516-8780)
- Fernando José de Sá Pereira Guimarães (ORCID: https://orcid.org/0000-0002-6260-0875)
Institutions
- Universidade Federal de Minas Gerais (BR)
- Universidade do Porto (PT)
- Universidade de Pernambuco (BR)
Publication Details
- Journal
- Medical Sciences
- Published
- 2025-11-14
- DOI
- https://doi.org/10.3390/medsci13040268
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00