Patients’ Concerns for Hormone-Replacement Therapy for Menopause

71 subjects in total completed the survey. 25 (35%) have never used HRT, and 46 (65%) have used it before. 17 (24%) individuals stated that concerns regarding cancer were central to decision-making on whether they opted to utilize HRT. Possible cancer risk was the most common concern (34, 48%) among the entire study population. The difference between the two groups was not significant regarding specific concerns and reasons as to why they did or did not receive this treatment for menopause. For the Menopause Rating Scale (MRS), the non-HRT group (Group 1) mean was 7.79, and the HRT group (Group 2) mean was 15.07. This difference was significant (two-tailed p = 0.0009). Conclusions: Findings from this study show there is still a large proportion of women concerned about risks of HRT especially regarding cancer. Future studies aimed at addressing significance in HRT's effect on osteoporosis, cardiovascular disease, and more that impact the morbidity and mortality of menopausal women could be vital to finding a unified stance on this topic.

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Publication Details

Journal
Cureus
Published
2025-11-12
DOI
https://doi.org/10.7759/cureus.96709
Primary Topic
Menopause: Health Impacts and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Patients’ Concerns for Hormone-Replacement Therapy for Menopause

K. Distler, Joshua C Hollingsworth, Denae Kappers
Cureus
Menopause: Health Impacts and Treatments
article

Patients’ Concerns for Hormone-Replacement Therapy for Menopause

K. Distler, Joshua C Hollingsworth, Denae Kappers
article en

Abstract

71 subjects in total completed the survey. 25 (35%) have never used HRT, and 46 (65%) have used it before. 17 (24%) individuals stated that concerns regarding cancer were central to decision-making on whether they opted to utilize HRT. Possible cancer risk was the most common concern (34, 48%) among the entire study population. The difference between the two groups was not significant regarding specific concerns and reasons as to why they did or did not receive this treatment for menopause. For the Menopause Rating Scale (MRS), the non-HRT group (Group 1) mean was 7.79, and the HRT group (Group 2) mean was 15.07. This difference was significant (two-tailed p = 0.0009). Conclusions: Findings from this study show there is still a large proportion of women concerned about risks of HRT especially regarding cancer. Future studies aimed at addressing significance in HRT's effect on osteoporosis, cardiovascular disease, and more that impact the morbidity and mortality of menopausal women could be vital to finding a unified stance on this topic.

CureusVol. 17(11)
Park Avenue Dermatology (US), Auburn University (US)
HCA Healthcare
Openalex Percentile: Top 54%
Menopause: Health Impacts and Treatments
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