Multiple myeloma presenting as a giant osteolytic skull mass: Surgical challenges and pitfalls – A case report

Giant exophytic skull lesions due to MM are rare and often mimic other neoplastic conditions. This case underscores the importance of early recognition, thorough diagnostic workup, and a multidisciplinary treatment approach. Radical neurosurgical resection combined with systemic oncological therapy is essential to optimize patient outcomes in such uncommon but aggressive presentations.

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Publication Details

Journal
Surgical Neurology International
Published
2025-11-14
DOI
https://doi.org/10.25259/sni_831_2025
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Multiple myeloma presenting as a giant osteolytic skull mass: Surgical challenges and pitfalls – A case report

Muhammad Mukhtar Khan, Esraa Mohamed Abdullah Elameen, Shahd H I Abbastanira, Modar Mouhsen Monther
Surgical Neurology International
Multiple Myeloma Research and Treatments
article

Multiple myeloma presenting as a giant osteolytic skull mass: Surgical challenges and pitfalls – A case report

Muhammad Mukhtar Khan, Esraa Mohamed Abdullah Elameen, Shahd H I Abbastanira, Modar Mouhsen Monther
article en

Abstract

Giant exophytic skull lesions due to MM are rare and often mimic other neoplastic conditions. This case underscores the importance of early recognition, thorough diagnostic workup, and a multidisciplinary treatment approach. Radical neurosurgical resection combined with systemic oncological therapy is essential to optimize patient outcomes in such uncommon but aggressive presentations.

Surgical Neurology InternationalVol. 16
Dubai Health Authority (AE), Rashid Hospital (AE), Dubai Hospital (AE), Zayed Military Hospital (AE)
Openalex Percentile: Top 55%
Multiple Myeloma Research and Treatments
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