Immune profiling and prognosis implications in severe fever with thrombocytopenia syndrome with and without hemophagocytic lymphohistiocytosis

SFTS complicated by HLH is characterized by immune dysregulation, high viral burden, and increased mortality. Early recognition of HLH and immune-virological surveillance may aid risk stratification and improve patient outcomes.

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Publication Details

Journal
Travel Medicine and Infectious Disease
Published
2025-11-01
DOI
https://doi.org/10.1016/j.tmaid.2025.102940
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Immune profiling and prognosis implications in severe fever with thrombocytopenia syndrome with and without hemophagocytic lymphohistiocytosis

Siyu Zou, Wei Wei, Yun Wang, Feng Wang et al.
Travel Medicine and Infectious Disease
Autoimmune and Inflammatory Disorders Research
article

Immune profiling and prognosis implications in severe fever with thrombocytopenia syndrome with and without hemophagocytic lymphohistiocytosis

Siyu Zou, Wei Wei, Yun Wang, Feng Wang, Ting Wang, Shiji Wu, Hongyan Hou, Ming Huang, Danning Xu
article en

Abstract

SFTS complicated by HLH is characterized by immune dysregulation, high viral burden, and increased mortality. Early recognition of HLH and immune-virological surveillance may aid risk stratification and improve patient outcomes.

Travel Medicine and Infectious DiseaseVol. 68
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 55%
Autoimmune and Inflammatory Disorders Research
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Immune profiling and prognosis implications in severe fever with thrombocytopenia syndrome with and without hemophagocytic lymphohistiocytosis — Siyu Zou, Wei Wei, et al. · Travel Medicine and Infectious Disease (2025) | TGRS Research Map | TGRS